HitPredict

Interactor 1: TBC12 (O60347)
TBC1 domain family member 12
Gene: TBC1D12

Interactor 2: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 775 Hs			1 218
+	Hs
		233036 TBC12_HUMAN (1-775): 0: 801: 100.00		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		1079972 TBC14_HUMAN (198-774): 6.65e-146: 445: 57.73		RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26
+	Hs
		914423 TBC14_HUMAN (198-774): 6.65e-146: 445: 57.73		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		232698 TBCD4_HUMAN (198-774): 2.1e-107: 358: 18.23		RAB2B_HUMAN (10-218): 1.65e-82: 246: 51.87
+	Dm
		1197045 Q9VPL5_DROME (175-747): 3.35e-100: 327: 17.67		Q86BK8_DROME (3-218): 6.99e-93: 273: 56.94
+	Os
		1130873 Q5SMT0_ORYSJ (266-745): 3.27e-99: 323: 15.98		Q6YY17_ORYSJ (9-197): 1.31e-91: 268: 55.03
+	Hs
		895106 TB10B_HUMAN (217-774): 2.57e-88: 297: 17.77		RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92
+	Os
		772871 Q5SMT0_ORYSJ (266-745): 3.27e-99: 323: 15.98		RIC2_ORYSJ (1-217): 1.78e-82: 246: 38.99
+	Hs
		918951 TBC17_HUMAN (206-772): 3.53e-97: 317: 16.04		RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43
+	Hs
		914176 TBCD1_HUMAN (226-771): 2.39e-91: 312: 17.90		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		592076 RBGP1_HUMAN (360-774): 3.62e-84: 291: 20.52		RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00
+	Hs
		914482 RBGP1_HUMAN (360-774): 3.62e-84: 291: 20.52		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		592065 TBD2B_HUMAN (288-774): 7.22e-80: 277: 18.34		RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00
+	Hs
		234370 EVI5_HUMAN (330-768): 1.12e-83: 285: 20.85		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		234378 EVI5_HUMAN (330-768): 1.12e-83: 285: 20.85		RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26
+	Dd
		332387 TBC12_DICDI (362-748): 5.88e-88: 286: 35.51		RAB14_DICDI (6-184): 1.48e-83: 248: 64.80
+	Hs
		914465 TBD2B_HUMAN (288-774): 7.22e-80: 277: 18.34		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		914275 EVI5L_HUMAN (372-768): 3.54e-80: 275: 22.08		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Dm
		185710 Q9VPL5_DROME (175-747): 3.35e-100: 327: 17.67		O18335_DROME (5-185): 7.23e-54: 173: 50.55
+	Dd
		332388 TBC12_DICDI (362-748): 5.88e-88: 286: 35.51		RB11A_DICDI (1-218): 3.69e-52: 169: 41.74