HitPredict

Interactor 1: HBP1 (O60381)
HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1)
Gene: HBP1

Interactor 2: RMD5A (Q9H871)
E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A)
Gene: RMND5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	29911972, 26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 514 Hs			1 391
+	Hs
		233861 HBP1_HUMAN (1-514): 0: 889: 100.00		MAEA_HUMAN (25-390): 1.22e-111: 334: 20.05
+	Hs
		233905 HBP1_HUMAN (1-514): 0: 889: 100.00		GID8_HUMAN (114-280): 5.61e-39: 141: 17.54
+	Hs
		233879 HBP1_HUMAN (1-514): 0: 889: 100.00		RANB9_HUMAN (87-214): 3.61e-11: 66.7: 16.41
+	Hs
		818473 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		RMD5A_HUMAN (1-391): 2.58e-160: 457: 100.00
+	Hs
		818345 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		RMD5B_HUMAN (1-391): 2.2e-152: 437: 69.72
+	Hs
		818188 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		MAEA_HUMAN (25-390): 1.22e-111: 334: 20.05
+	Hs
		818524 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		GID8_HUMAN (114-280): 5.61e-39: 141: 17.54
+	Hs
		1301799 HM20A_HUMAN (335-513): 3.32e-32: 128: 17.68		RANB9_HUMAN (87-214): 3.61e-11: 66.7: 16.41
+	Hs
		818375 SOX2_HUMAN (403-511): 1.47e-32: 128: 28.44		RANB9_HUMAN (87-214): 3.61e-11: 66.7: 16.41