HitPredict

Interactor 1: PEPL (O60437)
Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)
Gene: PPL

Interactor 2: DCA10 (Q5QP82)
DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32)
Gene: DCAF10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1756 Hs			1 559
+	Hs
		234241 PEPL_HUMAN (1-1756): 3.44e-127: 441: 100.00		WDR5B_HUMAN (12-325): 5.26e-48: 171: 12.50
+	Hs
		551731 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		DCA10_HUMAN (1-559): 4.4e-96: 305: 100.00
+	Hs
		728492 MYH11_HUMAN (1-836): 1.44e-34: 147: 9.73		POC1A_HUMAN (286-557): 1.87e-37: 144: 10.58
+	Hs
		903240 PLEC_HUMAN (1-1360): 9.93e-42: 171: 10.15		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		724753 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64
+	Hs
		551766 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		WDR5B_HUMAN (12-325): 5.26e-48: 171: 12.50
+	Hs
		1061226 NUMA1_HUMAN (2-783): 1.46e-15: 85.3: 10.87		KTNB1_HUMAN (15-264): 2.16e-32: 133: 9.16
+	Hs
		1313659 MACF1_HUMAN (498-1680): 1.71e-12: 75.4: 12.90		KTNB1_HUMAN (15-264): 2.16e-32: 133: 9.16
+	Hs
		792973 CENPE_HUMAN (723-1718): 1.85e-27: 124: 11.52		LIS1_HUMAN (400-555): 6.63e-16: 81.7: 12.82
+	Hs
		903212 SPTN1_HUMAN (4-1191): 1.92e-18: 94.9: 10.52		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		551659 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64
+	Hs
		1061204 NUMA1_HUMAN (2-783): 1.46e-15: 85.3: 10.87		SNR40_HUMAN (333-557): 6.41e-23: 102: 9.21
+	Hs
		921592 GRDN_HUMAN (1065-1598): 6.32e-11: 70.1: 23.13		GBB2_HUMAN (184-555): 2.19e-26: 111: 13.64
+	Hs
		903233 GOGB1_HUMAN (1144-1736): 3.26e-14: 81: 12.80		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		551655 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		903607 MACF1_HUMAN (498-1680): 1.71e-12: 75.4: 12.90		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		551854 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		NLE1_HUMAN (390-556): 5.65e-18: 89: 13.30
+	Hs
		551632 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		LIS1_HUMAN (400-555): 6.63e-16: 81.7: 12.82
+	Hs
		551882 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		WSB1_HUMAN (171-322): 3.49e-13: 73.6: 22.56
+	Hs
		551858 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		WSB2_HUMAN (171-348): 7.11e-12: 69.4: 23.56