HitPredict

Interactor 1: PEPL (O60437)
Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)
Gene: PPL

Interactor 2: WDR5B (Q86VZ2)
WD repeat-containing protein 5B
Gene: WDR5B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1756 Hs			1 330
+	Hs
		903240 PLEC_HUMAN (1-1360): 9.93e-42: 171: 10.15		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		1068625 PLEC_HUMAN (1-1360): 9.93e-42: 171: 10.15		FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40
+	Hs
		724952 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40
+	Hs
		903212 SPTN1_HUMAN (4-1191): 1.92e-18: 94.9: 10.52		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		903233 GOGB1_HUMAN (1144-1736): 3.26e-14: 81: 12.80		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		1061201 NUMA1_HUMAN (2-783): 1.46e-15: 85.3: 10.87		FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40
+	Hs
		551655 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		903607 MACF1_HUMAN (498-1680): 1.71e-12: 75.4: 12.90		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		1281478 MACF1_HUMAN (498-1680): 1.71e-12: 75.4: 12.90		FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40
+	Hs
		903399 MY18A_HUMAN (485-984): 1.11e-10: 69.2: 12.86		WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21
+	Hs
		551766 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		WDR5B_HUMAN (2-282): 1.14e-90: 275: 29.97
+	Hs
		1268063 MY18A_HUMAN (485-984): 1.11e-10: 69.2: 12.86		FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40
+	Hs
		197084 CP250_HUMAN (1-1328): 4.6e-43: 175: 11.06		PRP4_HUMAN (125-330): 6.22e-50: 175: 22.43
+	Hs
		792973 CENPE_HUMAN (723-1718): 1.85e-27: 124: 11.52		LIS1_HUMAN (1-113): 3.92e-31: 122: 20.30
+	Hs
		728492 MYH11_HUMAN (1-836): 1.44e-34: 147: 9.73		POC1A_HUMAN (2-71): 6.73e-17: 82.7: 22.86
+	Hs
		551723 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		SMU1_HUMAN (39-326): 3.4e-36: 138: 29.70
+	Hs
		551854 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		NLE1_HUMAN (193-329): 6.37e-33: 128: 22.38
+	Hs
		551632 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		LIS1_HUMAN (1-113): 3.92e-31: 122: 20.30
+	Hs
		1061204 NUMA1_HUMAN (2-783): 1.46e-15: 85.3: 10.87		SNR40_HUMAN (197-329): 1.9e-28: 114: 27.61
+	Hs
		1061224 NUMA1_HUMAN (2-783): 1.46e-15: 85.3: 10.87		WDR83_HUMAN (202-326): 1.67e-11: 65.9: 33.60