HitPredict

Interactor 1: PEPL (O60437)
Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)
Gene: PPL

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	16713569
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1756 Hs			1 1102
+	Hs
		1273841 CP250_HUMAN (1-1328): 4.6e-43: 175: 11.06		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1068624 PLEC_HUMAN (1-1360): 9.93e-42: 171: 10.15		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		724949 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		969609 CENPE_HUMAN (723-1718): 1.85e-27: 124: 11.52		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273954 MYH13_HUMAN (7-857): 7.73e-27: 122: 8.83		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1061196 NUMA1_HUMAN (2-783): 1.46e-15: 85.3: 10.87		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1059249 GOGB1_HUMAN (1144-1736): 3.26e-14: 81: 12.80		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		551797 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273964 MACF1_HUMAN (498-1680): 1.71e-12: 75.4: 12.90		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		974121 DYST_HUMAN (724-1629): 8.16e-09: 63.1: 11.55		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		528398 MYH6_HUMAN (1-1003): 1.54e-38: 160: 9.09		UBP24_HUMAN (200-587): 2.93e-95: 337: 24.41
+	Hs
		725051 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13
+	Mm
		1113526 MYH9_MOUSE (13-946): 1.66e-20: 101: 9.74		UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45
+	Mm
		82759 B9EKJ1_MOUSE (4-1212): 8.41e-19: 96.1: 10.31		UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45
+	Hs
		551869 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43
+	Mm
		93872 E9QPE7_MOUSE (1149-1654): 1.21e-12: 75.8: 18.38		UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45
+	Mm
		1113630 MY18A_MOUSE (465-1059): 5.4e-12: 73.5: 12.64		UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45
+	Mm
		1113452 SPTB2_MOUSE (506-1755): 2.99e-10: 67.9: 9.67		UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45
+	Hs
		1113861 GRDN_HUMAN (1065-1598): 6.32e-11: 70.1: 23.13		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13