HitPredict

Interactor 1: PEPL (O60437)
Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)
Gene: PPL

Interactor 2: CLMN (Q96JQ2)
Calmin (Calponin-like transmembrane domain protein)
Gene: CLMN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1756 Hs			1 1002
+	Hs
		521484 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		ACTN1_HUMAN (4-638): 4e-136: 433: 19.42
+	Hs
		211515 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		ACTN4_HUMAN (12-642): 7.65e-124: 401: 19.36
+	Rn
		555261 SPTN1_RAT (4-1212): 4.9e-19: 96.8: 10.10		ACTN1_RAT (4-638): 1.12e-136: 435: 19.42
+	Hs
		724781 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		SPTB2_HUMAN (6-505): 7.53e-113: 386: 25.64
+	Hs
		164575 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		SPTN2_HUMAN (16-505): 1.34e-109: 377: 26.56
+	Hs
		506818 SPTN1_HUMAN (4-1191): 1.92e-18: 94.9: 10.52		SPTB1_HUMAN (3-529): 3.6e-122: 413: 24.16
+	Rn
		555258 SPTN1_RAT (4-1212): 4.9e-19: 96.8: 10.10		Q6XD99_RAT (6-529): 3.78e-116: 396: 24.48
+	Hs
		963320 SPTN1_HUMAN (4-1191): 1.92e-18: 94.9: 10.52		SPTB2_HUMAN (6-505): 7.53e-113: 386: 25.64
+	Hs
		164614 SPTN1_HUMAN (4-1191): 1.92e-18: 94.9: 10.52		SPTN2_HUMAN (16-505): 1.34e-109: 377: 26.56
+	Hs
		164603 SPTN2_HUMAN (73-1521): 7.79e-13: 76.4: 12.03		SPTB2_HUMAN (6-505): 7.53e-113: 386: 25.64
+	Hs
		1045513 SPTN1_HUMAN (4-1191): 1.92e-18: 94.9: 10.52		SPTN4_HUMAN (14-400): 4.7e-96: 337: 29.74
+	Hs
		1068536 PLEC_HUMAN (1-1360): 9.93e-42: 171: 10.15		PLEC_HUMAN (29-293): 2.43e-37: 155: 38.72
+	Hs
		1068700 PLEC_HUMAN (1-1360): 9.93e-42: 171: 10.15		MACF1_HUMAN (29-293): 1.96e-36: 152: 39.47
+	Hs
		724839 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		PLEC_HUMAN (29-293): 2.43e-37: 155: 38.72
+	Hs
		725073 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		MACF1_HUMAN (29-293): 1.96e-36: 152: 39.47
+	Hs
		1045418 SPTN1_HUMAN (4-1191): 1.92e-18: 94.9: 10.52		PLEC_HUMAN (29-293): 2.43e-37: 155: 38.72
+	Hs
		1061289 NUMA1_HUMAN (2-783): 1.46e-15: 85.3: 10.87		MACF1_HUMAN (29-293): 1.96e-36: 152: 39.47
+	Mm
		93578 DESP_MOUSE (1619-1753): 8.47e-14: 79.5: 31.62		PLEC_MOUSE (29-293): 7.21e-37: 154: 38.29
+	Hs
		1068551 FIL1L_HUMAN (1251-1640): 4.38e-13: 77: 24.94		PLEC_HUMAN (29-293): 2.43e-37: 155: 38.72