Interactor 1: BRNP1 (O60477)
BMP/retinoic acid-inducible neural-specific protein 1 (Deleted in bladder cancer protein 1)
Gene: BRINP1

Interactor 2: SIR1 (Q96EB6)
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]
Gene: SIRT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.55 0.700

The method score is based on:

Property Details
Experiments 26113041, 18235502, 21030595, 23382074, 18235501, 22446626
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0045786 - negative regulation of cell cycle
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024