HitPredict

Interactor 1: MPZL2 (O60487)
Myelin protein zero-like protein 2 (Epithelial V-like antigen 1)
Gene: MPZL2

Interactor 2: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28065597
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Furin-like~V-set, GF_recep_IV~V-set, Recep_L_domain~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0098609 - cell-cell adhesion
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 1210
+	Hs
		338270 CXAR_HUMAN (8-213): 1.22e-34: 127: 20.00		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		339104 BTNL2_HUMAN (25-196): 3.17e-23: 98.3: 12.64		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		234735 MPZL2_HUMAN (1-215): 2.29e-59: 187: 100.00		ERBB2_HUMAN (5-1200): 0: 1111: 48.49
+	Hs
		234736 MPZL2_HUMAN (1-215): 2.29e-59: 187: 100.00		INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87
+	Hs
		665204 CXAR_HUMAN (8-213): 1.22e-34: 127: 20.00		EPHA2_HUMAN (665-1016): 5.77e-117: 389: 32.79
+	Hs
		411521 BTNL2_HUMAN (25-196): 3.17e-23: 98.3: 12.64		INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87
+	Hs
		234737 MPZL2_HUMAN (1-215): 2.29e-59: 187: 100.00		IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47