HitPredict

Interactor 1: CUBN (O60494)
Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)
Gene: CUBN

Interactor 2: CUBN (O60494)
Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)
Gene: CUBN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 20237569
Identification Methods pull down, molecular sieving
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CUB~CUB, CUB~EGF_CA, EGF~EGF, EGF~EGF_CA, EGF_3~EGF_CA, EGF_CA~EGF_CA
Common GO terms GO:0001894 - tissue homeostasis
GO:0005509 - calcium ion binding
GO:0005765 - lysosomal membrane
GO:0005768 - endosome
GO:0005783 - endoplasmic reticulum
and 24 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 3623
Hs

1 3623
+ Rn
+ Ss
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dr
+ Dr

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024