HitPredict

Interactor 1: STX10 (O60499)
Syntaxin-10 (Syn10)
Gene: STX10

Interactor 2: VPS45 (Q9NRW7)
Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45)
Gene: VPS45

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~Sec1
Common GO terms	GO:0000139 - Golgi membrane GO:0006886 - intracellular protein transport
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 249 Hs			1 570
+	Hs
		213020 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		VPS45_HUMAN (1-570): 0: 647: 100.00
+	Hs
		1345175 STX8_HUMAN (3-230): 5.49e-38: 134: 16.52		VPS45_HUMAN (1-570): 0: 647: 100.00
+	Hs
		169625 BET1_HUMAN (133-249): 2.91e-31: 113: 14.53		VPS45_HUMAN (1-570): 0: 647: 100.00
+	Hs
		235200 STX10_HUMAN (1-233): 1.52e-69: 215: 100.00		SCFD1_HUMAN (18-553): 2.28e-141: 425: 20.10
+	Hs
		212953 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		SCFD1_HUMAN (18-553): 2.28e-141: 425: 20.10
+	At
		1319854 SNP30_ARATH (52-222): 1.36e-25: 103: 14.94		KEULE_ARATH (8-562): 1.04e-156: 465: 21.14
+	Sc
		758048 TLG1_YEAST (2-232): 9.05e-31: 115: 19.05		VPS45_YEAST (1-549): 3.04e-152: 451: 36.33
+	Dm
		1096658 Q9VV76_DROME (5-235): 9.81e-35: 126: 14.72		SLY1_DROME (1-556): 1.77e-145: 435: 20.44
+	Hs
		1261668 STX8_HUMAN (3-230): 5.49e-38: 134: 16.52		SCFD1_HUMAN (18-553): 2.28e-141: 425: 20.10
+	Hs
		169556 BET1_HUMAN (133-249): 2.91e-31: 113: 14.53		SCFD1_HUMAN (18-553): 2.28e-141: 425: 20.10
+	Dm
		1096659 Q9VVX6_DROME (141-249): 3.83e-25: 97.6: 18.35		SLY1_DROME (1-556): 1.77e-145: 435: 20.44
+	Hs
		212997 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		VP33B_HUMAN (3-550): 1.22e-106: 334: 14.66
+	Sc
		605780 BET1_YEAST (108-245): 1.12e-24: 97.2: 16.31		SLY1_YEAST (12-560): 9.85e-129: 393: 19.11