HitPredict

Interactor 1: VINEX (O60504)
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)
Gene: SORBS3

Interactor 2: Q49AR9 (Q49AR9)
ANKS1A protein
Gene: ANKS1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 671 Hs			1 570
+	Hs
		235561 VINEX_HUMAN (1-671): 2.64e-132: 406: 100.00		ANS1A_HUMAN (1-493): 8.68e-149: 458: 92.90
+	Hs
		1115812 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		Q49AR9_HUMAN (1-570): 0: 574: 100.00
+	Hs
		1268487 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		ANS1A_HUMAN (1-493): 8.68e-149: 458: 92.90
+	Hs
		1268522 CD2AP_HUMAN (614-671): 8.75e-11: 67.2: 27.12		ANS1A_HUMAN (1-493): 8.68e-149: 458: 92.90
+	Mm
		1206695 ASAP1_MOUSE (260-668): 3.87e-18: 91.3: 14.73		ANS1B_MOUSE (1-497): 3.93e-137: 430: 52.65
+	Hs
		1191815 CD2AP_HUMAN (614-671): 8.75e-11: 67.2: 27.12		ANS1B_HUMAN (1-437): 4.42e-140: 438: 57.43
+	Mm
		1206702 ITSN1_MOUSE (450-671): 5.12e-10: 65: 13.60		ANS1B_MOUSE (1-497): 3.93e-137: 430: 52.65
+	Dm
		112569 M9ND00_DROME (44-544): 9.5e-32: 134: 15.98		NUMB_DROME (186-537): 3.26e-50: 183: 14.93
+	Mm
		292683 GRAP2_MOUSE (182-436): 6.06e-24: 105: 14.79		SHC1_MOUSE (146-570): 1.16e-53: 193: 13.92
+	Hs
		666109 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		SHC1_HUMAN (146-570): 9.09e-51: 185: 13.81
+	Hs
		269148 ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02		DAB1_HUMAN (232-533): 8.11e-53: 191: 15.53
+	Hs
		1263386 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		CSKI2_HUMAN (5-256): 2.18e-52: 195: 21.45
+	Mm
		957235 GRB2_MOUSE (615-669): 2.48e-14: 74.6: 28.57		SHC1_MOUSE (146-570): 1.16e-53: 193: 13.92
+	Hs
		269176 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		DAB1_HUMAN (232-533): 8.11e-53: 191: 15.53
+	Ce
		104725 SRBS1_CAEEL (182-671): 5.35e-11: 68.2: 11.88		Q93203_CAEEL (97-411): 1.33e-52: 195: 20.00
+	Ce
		283748 YKA7_CAEEL (444-670): 1.12e-15: 82.1: 12.88		CED6_CAEEL (233-508): 7.12e-49: 178: 18.28
+	Hs
		666105 SPTN1_HUMAN (511-671): 1.08e-12: 73.9: 9.94		SHC1_HUMAN (146-570): 9.09e-51: 185: 13.81
+	Rn
		924995 GRB2_RAT (616-669): 6.14e-14: 73.2: 29.09		SHC1_RAT (216-570): 7.81e-50: 180: 15.11
+	Hs
		1256289 SH3R3_HUMAN (81-579): 2.19e-16: 85.4: 11.58		JIP1_HUMAN (240-393): 2e-33: 137: 23.17