HitPredict

Interactor 1: VINEX (O60504)
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)
Gene: SORBS3

Interactor 2: RIN3 (Q8TB24)
Ras and Rab interactor 3 (Ras interaction/interference protein 3)
Gene: RIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32552912
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 671 Hs			1 985
+	Hs
		1251911 SRBS1_HUMAN (522-671): 2.49e-20: 98.4: 35.53		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		275213 GRAP2_HUMAN (182-436): 9.34e-19: 90.1: 12.83		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		1251947 PACN2_HUMAN (433-671): 4.38e-18: 89.7: 15.98		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		1251932 ITSN2_HUMAN (116-671): 3.14e-15: 82: 10.46		RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00
+	Hs
		235502 VINEX_HUMAN (1-671): 2.64e-132: 406: 100.00		RIN1_HUMAN (6-327): 3.07e-21: 101: 26.32
+	Hs
		203191 VINEX_HUMAN (1-671): 2.64e-132: 406: 100.00		SYNJ1_HUMAN (311-736): 7.31e-12: 71.8: 11.24
+	Hs
		1155935 SRBS1_HUMAN (522-671): 2.49e-20: 98.4: 35.53		Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19
+	Rn
		192744 SRBS2_RAT (56-671): 3.74e-63: 229: 27.36		SYNJ1_RAT (73-492): 6.56e-11: 68.7: 10.09
+	Hs
		1078842 ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02		Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19
+	Hs
		1155937 ITSN2_HUMAN (116-671): 3.14e-15: 82: 10.46		Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19
+	Hs
		1155933 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19
+	Hs
		203192 SRBS2_HUMAN (56-671): 2.3e-57: 212: 26.28		SYNJ1_HUMAN (311-736): 7.31e-12: 71.8: 11.24
+	Hs
		166049 ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02		SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77
+	Hs
		166056 ITSN2_HUMAN (116-671): 3.14e-15: 82: 10.46		SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77
+	Hs
		166055 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77
+	Hs
		1044770 ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02		RIN1_HUMAN (6-327): 3.07e-21: 101: 26.32
+	Hs
		203250 SRBS1_HUMAN (522-671): 2.49e-20: 98.4: 35.53		SYNJ1_HUMAN (311-736): 7.31e-12: 71.8: 11.24
+	Hs
		203262 PACN2_HUMAN (433-671): 4.38e-18: 89.7: 15.98		SYNJ1_HUMAN (311-736): 7.31e-12: 71.8: 11.24
+	Hs
		203228 ITSN1_HUMAN (434-671): 1.7e-15: 82.7: 15.02		SYNJ1_HUMAN (311-736): 7.31e-12: 71.8: 11.24
+	Hs
		203241 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		SYNJ1_HUMAN (311-736): 7.31e-12: 71.8: 11.24