HitPredict

Interactor 1: HNRPQ (O60506)
Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein)
Gene: SYNCRIP

Interactor 2: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26641092
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 623 Hs			1 475
+	Hs
		235877 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79
+	Mm
		936683 HNRPQ_MOUSE (1-623): 2.1e-140: 424: 99.68		ELAV1_MOUSE (149-471): 9.51e-73: 234: 14.58
+	Hs
		235827 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		202062 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00
+	Hs
		235862 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		202181 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79
+	Hs
		202142 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		235718 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		ELAV4_HUMAN (88-342): 7.66e-39: 146: 13.33
+	Mm
		857343 HNRPQ_MOUSE (1-623): 2.1e-140: 424: 99.68		TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70
+	Hs
		236122 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50
+	Hs
		202167 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		235835 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78
+	Hs
		235683 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35
+	Hs
		47781 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79
+	Hs
		47769 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Mm
		857321 Q3UZI0_MOUSE (49-623): 8.45e-99: 315: 78.66		TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70
+	Hs
		202148 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78
+	Hs
		47766 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		TIAR_HUMAN (251-473): 6.95e-33: 130: 14.67
+	Hs
		47770 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78
+	Hs
		47742 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35