HitPredict

Interactor 1: HNRPQ (O60506)
Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein)
Gene: SYNCRIP

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	35271311, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0006396 - RNA processing GO:1990904 - ribonucleoprotein complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 623 Hs			1 644
+	Hs
		235683 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		202148 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		47770 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		47742 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		474021 PAB4L_HUMAN (163-430): 1.84e-57: 199: 22.97		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		516495 PABP4_HUMAN (152-621): 1.53e-53: 195: 17.26		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516339 PABP1_HUMAN (152-609): 3.29e-52: 191: 16.08		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516689 PABP1_HUMAN (152-609): 3.29e-52: 191: 16.08		PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98
+	Mm
		857343 HNRPQ_MOUSE (1-623): 2.1e-140: 424: 99.68		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12
+	Hs
		202053 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		202248 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Mm
		857321 Q3UZI0_MOUSE (49-623): 8.45e-99: 315: 78.66		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12
+	Hs
		516355 PABP1_HUMAN (152-609): 3.29e-52: 191: 16.08		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		474034 PAB4L_HUMAN (163-430): 1.84e-57: 199: 22.97		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		516635 PABP1_HUMAN (152-609): 3.29e-52: 191: 16.08		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Zm
		8143 A0A1D6ELH4_MAIZE (128-618): 3.77e-50: 186: 14.31		A0A1D6ELH4_MAIZE (1-89): 1.11e-15: 82.6: 30.34
+	Mm
		665745 PABP1_MOUSE (152-609): 4.26e-52: 191: 16.08		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12