HitPredict

Interactor 1: HNRPQ (O60506)
Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein)
Gene: SYNCRIP

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	29845934, 18281698
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008380 - RNA splicing and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 623 Hs			1 582
+	Hs
		202191 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		235835 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		235683 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		235921 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		235981 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		236105 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Mm
		857343 HNRPQ_MOUSE (1-623): 2.1e-140: 424: 99.68		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		202148 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		235877 HNRPQ_HUMAN (1-623): 4.45e-141: 425: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Mm
		936683 HNRPQ_MOUSE (1-623): 2.1e-140: 424: 99.68		ELAV1_MOUSE (92-211): 6.43e-13: 71.9: 22.50
+	Hs
		202248 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	At
		285478 PABP8_ARATH (71-579): 1.08e-73: 251: 16.24		LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20
+	Hs
		47770 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		47742 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		47799 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Mm
		857321 Q3UZI0_MOUSE (49-623): 8.45e-99: 315: 78.66		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		202181 HNRPR_HUMAN (3-623): 8.08e-111: 348: 77.09		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		47827 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		47798 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		47781 RBM47_HUMAN (111-549): 6.72e-82: 270: 44.94		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50