HitPredict

Interactor 1: PRP17 (O60508)
Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3) (PRP17 homolog) (hPRP17)
Gene: CDC40

Interactor 2: SNR40 (Q96DI7)
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Gene: SNRNP40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 33961781, 37689310
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0016607 - nuclear speck
GO:0071007 - U2-type catalytic step 2 spliceosome
and 1 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 579
Hs

1 357
+ Dm
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
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+ Mm
+ Hs
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024