HitPredict

Interactor 1: PRP17 (O60508)
Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3) (PRP17 homolog) (hPRP17)
Gene: CDC40

Interactor 2: RALY (Q9UKM9)
RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog)
Gene: RALY

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 306
+	Hs
		236237 PRP17_HUMAN (30-579): 1.21e-144: 431: 100.00		RALYL_HUMAN (1-224): 3.08e-105: 310: 64.83
+	Hs
		236185 PRP17_HUMAN (30-579): 1.21e-144: 431: 100.00		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		236174 PRP17_HUMAN (30-579): 1.21e-144: 431: 100.00		HNRC1_HUMAN (6-297): 1.05e-98: 293: 43.43
+	Hs
		71042 PRP17_HUMAN (30-579): 1.21e-144: 431: 100.00		HNRC2_HUMAN (6-218): 4.64e-97: 289: 52.07
+	Hs
		1230140 DAW1_HUMAN (87-488): 5.86e-80: 259: 14.39		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		1288377 SNR40_HUMAN (324-579): 4.45e-65: 218: 19.85		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		903592 WDR5_HUMAN (95-445): 1.64e-63: 213: 15.54		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		432626 WDR5_HUMAN (95-445): 1.64e-63: 213: 15.54		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		432847 FBXW7_HUMAN (445-579): 1.27e-22: 104: 17.78		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38