HitPredict

Interactor 1: PRP17 (O60508)
Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3) (PRP17 homolog) (hPRP17)
Gene: CDC40

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.910

The method score is based on:

Property Details
Experiments 28514442, 29395067, 33961781, 22365833
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005654 - nucleoplasm
GO:0016607 - nuclear speck
GO:0071007 - U2-type catalytic step 2 spliceosome
GO:0071013 - catalytic step 2 spliceosome
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 579
Hs

1 504
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024