HitPredict

Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.641

Property	Details
Experiments	19407811, 24825348
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, acetylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005634 - nucleus GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 832
+	Hs
		236962 BUB1B_HUMAN (1-1050): 0: 826: 100.00		KAT2A_HUMAN (63-832): 0: 1056: 73.42
+	Hs
		681962 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		KAT2B_HUMAN (72-832): 0: 1128: 100.00
+	Hs
		681961 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		KAT2A_HUMAN (63-832): 0: 1056: 73.42
+	Hs
		211007 BUB1_HUMAN (53-1042): 1.59e-170: 531: 19.04		BPTF_HUMAN (725-825): 5.43e-35: 146: 47.53
+	Hs
		170273 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		TIF1A_HUMAN (641-827): 1.04e-38: 157: 22.22
+	Hs
		631635 AURKC_HUMAN (760-1016): 3.71e-40: 152: 16.48		BRD2_HUMAN (663-830): 1.89e-35: 146: 23.37
+	Hs
		160280 AURKA_HUMAN (671-986): 1.25e-38: 151: 16.01		BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15