HitPredict

Interactor 1: PLOD3 (O60568)
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)]
Gene: PLOD3

Interactor 2: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 738 Hs			1 645
+	Hs
		129887 PLOD2_HUMAN (19-738): 0: 1217: 58.75		PDIA4_HUMAN (1-645): 0: 571: 100.00
+	Hs
		531801 PLOD1_HUMAN (32-738): 0: 1184: 59.38		PDIA4_HUMAN (1-645): 0: 571: 100.00
+	Hs
		237092 PLOD3_HUMAN (1-738): 0: 1310: 100.00		DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47
+	Hs
		972781 PLOD1_HUMAN (32-738): 0: 1184: 59.38		DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47
+	Hs
		671788 PLOD1_HUMAN (32-738): 0: 1184: 59.38		PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35
+	Hs
		531905 GT251_HUMAN (279-546): 1.17e-98: 319: 21.74		PDIA4_HUMAN (1-645): 0: 571: 100.00
+	Hs
		1220431 GT251_HUMAN (279-546): 1.17e-98: 319: 21.74		DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47