HitPredict

Interactor 1: PLOD3 (O60568)
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)]
Gene: PLOD3

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	30833792, 32409323, 22268729
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 738 Hs			1 293
+	Hs
		129945 PLOD2_HUMAN (19-738): 0: 1217: 58.75		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		972825 PLOD1_HUMAN (32-738): 0: 1184: 59.38		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		237137 PLOD3_HUMAN (1-738): 0: 1310: 100.00		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1239907 GT251_HUMAN (279-546): 1.17e-98: 319: 21.74		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1223337 GT252_HUMAN (283-546): 5.69e-96: 312: 27.80		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1133337 GT253_HUMAN (294-547): 1.65e-90: 296: 23.51		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00