Interactor 1: TLR5 (O60602)
Toll-like receptor 5 (Toll/interleukin-1 receptor-like protein 3)
Gene: TLR5

Interactor 2: TLR5 (O60602)
Toll-like receptor 5 (Toll/interleukin-1 receptor-like protein 3)
Gene: TLR5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 23155421
Identification Methods tox-r dimerization assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_1~LRR_1, LRR_1~LRR_8, LRR_8~LRR_8, TIR~TIR
Common GO terms GO:0002224 - toll-like receptor signaling pathway
GO:0004888 - transmembrane signaling receptor activity
GO:0005149 - interleukin-1 receptor binding
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
and 6 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 858
Hs

1 858
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024