Interactor 1: TLR2 (O60603)
Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
Gene: TLR2

Interactor 2: CLC7A (Q9BXN2)
C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (CD antigen CD369)
Gene: CLEC7A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 21899704, 18373632
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~Lectin_C
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0009986 - cell surface
GO:0010628 - positive regulation of gene expression
and 7 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 784
Hs

1 247
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024