HitPredict

Interactor 1: DIAP1 (O60610)
Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1)
Gene: DIAPH1

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~FH2
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005884 - actin filament GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1272 Hs			1 375
+	Hs
		237587 DIAP1_HUMAN (1-1272): 0: 953: 100.00		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		1122441 FMNL3_HUMAN (84-491): 3.5e-81: 290: 18.81		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		892064 DIAP3_HUMAN (755-1234): 1.41e-122: 411: 57.47		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		892135 DAAM1_HUMAN (52-557): 7.19e-99: 342: 22.74		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Dm
		361147 Q8SY43_DROME (763-1204): 5.34e-88: 314: 24.32		ACT2_DROME (2-375): 0: 596: 97.59
+	Sc
		773864 BNR1_YEAST (747-1217): 6.02e-82: 297: 21.23		ACT_YEAST (1-375): 0: 591: 88.80
+	Hs
		915429 FMNL3_HUMAN (84-491): 3.5e-81: 290: 18.81		ACTA_HUMAN (2-375): 0: 591: 94.12
+	Hs
		892145 FHOD1_HUMAN (25-581): 8.51e-72: 264: 13.38		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		930071 FHOD1_HUMAN (25-581): 8.51e-72: 264: 13.38		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		929974 FMNL2_HUMAN (68-653): 1.92e-65: 244: 14.36		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		891803 INF2_HUMAN (117-606): 5.39e-59: 224: 21.70		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		929884 INF2_HUMAN (117-606): 5.39e-59: 224: 21.70		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		932188 INF2_HUMAN (117-606): 5.39e-59: 224: 21.70		ACTC_HUMAN (2-375): 0: 592: 94.12