HitPredict

Interactor 1: DIAP1 (O60610)
Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1)
Gene: DIAPH1

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.863

The method score is based on:

Property Details
Experiments 12773565, 31871319, 18218625
Identification Methods pull down, two hybrid, affinity chromatography technology, surface plasmon resonance
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030036 - actin cytoskeleton organization
GO:0030667 - secretory granule membrane
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1272
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024