HitPredict

Interactor 1: TSN2 (O60636)
Tetraspanin-2 (Tspan-2) (Tetraspan NET-3)
Gene: TSPAN2

Interactor 2: CD63 (P08962)
CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63)
Gene: CD63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005654 - nucleoplasm GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 221 Hs			1 238
+	Hs
		446010 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD63_HUMAN (1-238): 2.68e-68: 211: 100.00
+	Hs
		602239 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		TSN5_HUMAN (7-235): 4.96e-63: 199: 25.20
+	Hs
		237719 TSN2_HUMAN (1-221): 4.08e-53: 171: 100.00		CD151_HUMAN (3-232): 2.85e-60: 191: 28.22
+	Hs
		602230 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD151_HUMAN (3-232): 2.85e-60: 191: 28.22
+	Hs
		602271 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		TSN14_HUMAN (11-235): 5.91e-59: 189: 27.60
+	Hs
		279368 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		TSN9_HUMAN (4-233): 2.1e-57: 184: 30.04
+	Hs
		819445 TSN5_HUMAN (8-218): 6.03e-49: 162: 23.44		CD151_HUMAN (3-232): 2.85e-60: 191: 28.22
+	Hs
		237716 TSN2_HUMAN (1-221): 4.08e-53: 171: 100.00		CD9_HUMAN (1-238): 1.72e-54: 176: 24.49
+	Hs
		279369 TSN5_HUMAN (8-218): 6.03e-49: 162: 23.44		TSN9_HUMAN (4-233): 2.1e-57: 184: 30.04
+	Hs
		602216 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD9_HUMAN (1-238): 1.72e-54: 176: 24.49
+	Hs
		602222 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD82_HUMAN (4-234): 1.91e-52: 172: 24.13
+	Hs
		602238 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD81_HUMAN (1-234): 5.88e-53: 172: 21.63
+	Hs
		583857 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD53_HUMAN (1-233): 2.61e-50: 165: 27.04
+	Hs
		237703 TSN2_HUMAN (1-221): 4.08e-53: 171: 100.00		TSN3_HUMAN (4-236): 4.09e-48: 160: 29.17
+	Hs
		237706 TSN2_HUMAN (1-221): 4.08e-53: 171: 100.00		TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97
+	Hs
		156131 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		TSN4_HUMAN (4-231): 1.61e-48: 161: 29.87
+	Hs
		326023 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97
+	Hs
		209300 TSN6_HUMAN (8-218): 3.56e-50: 165: 20.26		TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97
+	Hs
		326051 TSN5_HUMAN (8-218): 6.03e-49: 162: 23.44		TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97