HitPredict

Interactor 1: TSN3 (O60637)
Tetraspanin-3 (Tspan-3) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8)
Gene: TSPAN3

Interactor 2: RN149 (Q8NC42)
E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)
Gene: RNF149

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 36610398
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 253 Hs			1 400
+	Hs
		1240718 TSN17_HUMAN (7-238): 7.27e-62: 197: 21.43		RN149_HUMAN (1-400): 4.22e-129: 378: 100.00
+	Hs
		446043 CD63_HUMAN (4-246): 2.53e-57: 184: 29.63		RN149_HUMAN (1-400): 4.22e-129: 378: 100.00
+	Hs
		887900 CD81_HUMAN (4-243): 1.66e-53: 174: 18.95		RN149_HUMAN (1-400): 4.22e-129: 378: 100.00
+	Mm
		192880 CD151_MOUSE (2-238): 1.24e-55: 180: 27.69		RN128_MOUSE (11-387): 1.6e-93: 289: 39.69
+	Hs
		1204810 TSN17_HUMAN (7-238): 7.27e-62: 197: 21.43		GOLI_HUMAN (30-374): 2.45e-84: 264: 40.52
+	Hs
		207527 TSN3_HUMAN (1-253): 1.82e-66: 208: 100.00		RNF13_HUMAN (36-382): 3.56e-70: 227: 20.33
+	Hs
		207535 CD63_HUMAN (4-246): 2.53e-57: 184: 29.63		RNF13_HUMAN (36-382): 3.56e-70: 227: 20.33
+	Hs
		653107 CD82_HUMAN (1-243): 1.85e-58: 188: 26.72		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29