HitPredict

Interactor 1: TSN3 (O60637)
Tetraspanin-3 (Tspan-3) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8)
Gene: TSPAN3

Interactor 2: LPAR1 (Q92633)
Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2)
Gene: LPAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 253 Hs			1 364
+	Hs
		237789 TSN3_HUMAN (1-253): 1.82e-66: 208: 100.00		MC4R_HUMAN (55-328): 2.7e-73: 232: 26.67
+	Hs
		428955 TSN7_HUMAN (6-246): 1.36e-60: 193: 31.84		ADRB2_HUMAN (54-350): 1.7e-66: 217: 17.38
+	Hs
		237791 TSN3_HUMAN (1-253): 1.82e-66: 208: 100.00		OPRX_HUMAN (2-343): 2.72e-60: 200: 16.67
+	Hs
		686590 CD81_HUMAN (4-243): 1.66e-53: 174: 18.95		MC4R_HUMAN (55-328): 2.7e-73: 232: 26.67
+	Hs
		237784 TSN3_HUMAN (1-253): 1.82e-66: 208: 100.00		S1PR1_HUMAN (10-333): 3.19e-59: 197: 36.86
+	Hs
		326161 TSN15_HUMAN (9-238): 4.22e-51: 170: 20.41		LPAR1_HUMAN (1-364): 3.44e-73: 233: 100.00
+	Hs
		325999 TSN15_HUMAN (9-238): 4.22e-51: 170: 20.41		S1PR4_HUMAN (1-360): 9.27e-72: 230: 30.89
+	Hs
		783912 TSN7_HUMAN (6-246): 1.36e-60: 193: 31.84		5HT4R_HUMAN (46-348): 1.68e-61: 203: 19.46
+	Hs
		304708 TSN15_HUMAN (9-238): 4.22e-51: 170: 20.41		S1PR2_HUMAN (28-350): 3.48e-70: 225: 32.92
+	Hs
		326029 TSN15_HUMAN (9-238): 4.22e-51: 170: 20.41		AA2BR_HUMAN (45-327): 9.42e-70: 223: 23.45
+	Hs
		583929 CD53_HUMAN (1-242): 3.95e-49: 162: 26.45		LPAR3_HUMAN (22-354): 9.16e-73: 231: 50.75
+	Hs
		428997 CD81_HUMAN (4-243): 1.66e-53: 174: 18.95		ADRB2_HUMAN (54-350): 1.7e-66: 217: 17.38
+	Hs
		722930 CD81_HUMAN (4-243): 1.66e-53: 174: 18.95		ADA1A_HUMAN (28-340): 4.04e-65: 215: 17.09
+	Hs
		208446 TSN15_HUMAN (9-238): 4.22e-51: 170: 20.41		OX2R_HUMAN (10-359): 1.2e-66: 218: 16.29
+	Hs
		326031 TSN15_HUMAN (9-238): 4.22e-51: 170: 20.41		NK3R_HUMAN (13-364): 1.05e-63: 211: 15.85
+	Hs
		428918 CD9_HUMAN (4-243): 4.33e-49: 162: 18.37		ADRB2_HUMAN (54-350): 1.7e-66: 217: 17.38
+	Hs
		887838 CD81_HUMAN (4-243): 1.66e-53: 174: 18.95		5HT4R_HUMAN (46-348): 1.68e-61: 203: 19.46
+	Hs
		326021 TSN15_HUMAN (9-238): 4.22e-51: 170: 20.41		S1PR1_HUMAN (10-333): 3.19e-59: 197: 36.86
+	Hs
		326225 TSN15_HUMAN (9-238): 4.22e-51: 170: 20.41		LPAR2_HUMAN (23-364): 1.03e-59: 197: 53.06