Interactor 1: PDE8A (O60658)
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53)
Gene: PDE8A
Interactor 2: PDE8B (O95263)
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)
Gene: PDE8B
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PAS~PAS_9, PDEase_I~PDEase_I |
| Common GO terms | GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity GO:0005634 - nucleus GO:0005829 - cytosol GO:0006198 - cAMP catabolic process GO:0019933 - cAMP-mediated signaling and 4 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
