HitPredict

Interactor 1: KLH41 (O60662)
Kelch-like protein 41 (Kel-like protein 23) (Kelch repeat and BTB domain-containing protein 10) (Kelch-related protein 1) (Sarcosin)
Gene: KLHL41

Interactor 2: NEBU (P20929)
Nebulin
Gene: NEB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	30986853, 23414517
Identification Methods	fluorescent resonance energy transfer, two hybrid, homogeneous time resolved fluorescence, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 606 Hs			1 8525
+	Hs
		596221 KLH40_HUMAN (1-606): 2.28e-145: 436: 49.60		NEBU_HUMAN (1-8525): 0: 8652: 100.00
+	Hs
		238086 KLH41_HUMAN (1-606): 2.79e-160: 473: 100.00		NRAP_HUMAN (6777-8419): 3.73e-150: 519: 19.14
+	Hs
		1103160 KLH40_HUMAN (1-606): 2.28e-145: 436: 49.60		NRAP_HUMAN (6777-8419): 3.73e-150: 519: 19.14
+	Mm
		57601 KLH41_MOUSE (1-606): 1.55e-157: 466: 95.38		NRAP_MOUSE (1236-2688): 3.09e-134: 470: 17.85
+	Mm
		1194448 KLH40_MOUSE (1-606): 2.5e-148: 443: 50.24		NRAP_MOUSE (1236-2688): 3.09e-134: 470: 17.85
+	Mm
		1322078 KLH40_MOUSE (1-606): 2.5e-148: 443: 50.24		Q9JL91_MOUSE (7857-8198): 1.48e-11: 72.7: 22.78
+	Dm
		1363697 KLHDB_DROME (397-605): 9.8e-57: 203: 22.38		Q9VDF4_DROME (8070-8525): 9.71e-55: 205: 12.40
+	Hs
		1049206 KEAP1_HUMAN (396-605): 1.07e-49: 184: 23.47		SRC8_HUMAN (8096-8488): 8.57e-18: 93.5: 11.51
+	Hs
		235517 KLH26_HUMAN (384-605): 3.86e-31: 130: 16.16		VINEX_HUMAN (8153-8525): 1.64e-33: 143: 11.63
+	Dm
		1211907 Q9VK21_DROME (396-605): 2.14e-42: 163: 22.12		LASP1_DROME (7702-7839): 3.81e-09: 66.2: 20.86