HitPredict

Interactor 1: LMX1B (O60663)
LIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B)
Gene: LMX1B

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 402 Hs			1 375
+	Hs
		1122468 LHX4_HUMAN (1-113): 6.25e-21: 95.4: 17.95		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		1122525 LHX3_HUMAN (1-109): 1.24e-20: 94.6: 18.58		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		150545 ABLM1_HUMAN (43-216): 1.27e-21: 99.3: 19.21		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		150554 ABLM1_HUMAN (43-216): 1.27e-21: 99.3: 19.21		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		300997 ABLM3_HUMAN (56-250): 2.95e-18: 88.9: 19.61		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		300998 ABLM3_HUMAN (56-250): 2.95e-18: 88.9: 19.61		ACTS_HUMAN (2-375): 0: 592: 93.58