Interactor 1: REV3L (O60673)
DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (hREV3)
Gene: REV3L
Interactor 2: MD2L2 (Q9UI95)
Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7)
Gene: MAD2L2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11485998, 20088965, 21926160, 20164194, 30111544, 30022168, 30254264, 30154076, 10660610, 22303021, 20054135, 22859296, 22828282 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, x-ray crystallography, proximity labelling technology, molecular sieving, nuclear magnetic resonance, isothermal titration calorimetry |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_pol_B_exo1~HORMA |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016035 - zeta DNA polymerase complex GO:0042276 - error-prone translesion synthesis |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
