Interactor 1: JAK2 (O60674)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2

Interactor 2: INGR1 (P15260)
Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119)
Gene: IFNGR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 7673114, 21689637
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001774 - microglial cell activation
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0019221 - cytokine-mediated signaling pathway
GO:0032760 - positive regulation of tumor necrosis factor production
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1132
Hs

1 489
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024