Interactor 1: JAK2 (O60674)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2

Interactor 2: LEPR (P48357)
Leptin receptor (LEP-R) (HuB219) (OB receptor) (OB-R) (CD antigen CD295)
Gene: LEPR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 11585385
Identification Methods coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0019221 - cytokine-mediated signaling pathway
GO:0120162 - positive regulation of cold-induced thermogenesis
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1132
Hs

1 1165
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024