HitPredict

Interactor 1: MAFK (O60675)
Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit)
Gene: MAFK

Interactor 2: NF2L2 (Q16236)
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nrf-2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)
Gene: NFE2L2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 32296183, 32911434, 10747902, 33961781, 21988832, 23737527, unassigned1304
Identification Methods two hybrid, fluorescent resonance energy transfer, pull down, affinity chromatography technology, luminescence based mammalian interactome mapping, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_Maf~bZIP_Maf
Common GO terms GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 156
Hs

1 605
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Last updated: 15 Jul 2024