Interactor 1: MAFK (O60675)
Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit)
Gene: MAFK

Interactor 2: BACH2 (Q9BYV9)
Transcription regulator protein BACH2 (BTB and CNC homolog 2)
Gene: BACH2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.894

The method score is based on:

Property Details
Experiments 29459360, 32296183, 33961781, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_Maf~bZIP_Maf
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 156
Hs

1 841
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Last updated: 15 Jul 2024