HitPredict

Interactor 1: MAFK (O60675)
Transcription factor MafK (Erythroid transcription factor NF-E2 p18 subunit)
Gene: MAFK

Interactor 2: NF2L3 (Q9Y4A8)
Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3)
Gene: NFE2L3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.863

The method score is based on:

Property Details
Experiments 28514442, 10037736, 33961781
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_Maf~bZIP_Maf
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 156
Hs

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Last updated: 15 Jul 2024