HitPredict

Interactor 1: PEX10 (O60683)
Peroxisome biogenesis factor 10 (EC 2.3.2.27) (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10) (RING finger protein 69)
Gene: PEX10

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 158
+	Sc
		549834 PEX10_YEAST (6-324): 3.9e-51: 174: 22.86		UBC4_YEAST (1-156): 1.22e-72: 216: 35.90
+	Hs
		1282543 MUL1_HUMAN (2-325): 8.99e-34: 128: 18.24		UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42
+	Hs
		849394 MUL1_HUMAN (2-325): 8.99e-34: 128: 18.24		UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12
+	Hs
		919811 MUL1_HUMAN (2-325): 8.99e-34: 128: 18.24		UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07
+	Hs
		895867 MUL1_HUMAN (2-325): 8.99e-34: 128: 18.24		UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07
+	Hs
		282581 RNF8_HUMAN (99-318): 1.65e-29: 119: 16.02		UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12
+	Hs
		282607 RNF8_HUMAN (99-318): 1.65e-29: 119: 16.02		UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07
+	Hs
		930339 MUL1_HUMAN (2-325): 8.99e-34: 128: 18.24		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	At
		715137 RNG1L_ARATH (98-326): 1.66e-30: 119: 12.71		UBC9_ARATH (4-157): 8.98e-74: 219: 35.07
+	Hs
		829001 HLTF_HUMAN (77-319): 1.91e-34: 135: 17.34		UBE2A_HUMAN (1-154): 3.37e-67: 202: 41.56
+	Hs
		1282522 MUL1_HUMAN (2-325): 8.99e-34: 128: 18.24		UB2E2_HUMAN (3-156): 7.29e-69: 208: 33.77
+	Hs
		927752 HLTF_HUMAN (77-319): 1.91e-34: 135: 17.34		UBE2B_HUMAN (1-154): 1.37e-66: 201: 41.56
+	Hs
		1282320 MUL1_HUMAN (2-325): 8.99e-34: 128: 18.24		UB2E3_HUMAN (3-156): 2.14e-68: 207: 33.77
+	Hs
		282595 RNF8_HUMAN (99-318): 1.65e-29: 119: 16.02		UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07
+	At
		1228275 RNG1L_ARATH (98-326): 1.66e-30: 119: 12.71		UBC29_ARATH (4-156): 2.89e-71: 212: 35.95
+	Hs
		851860 MUL1_HUMAN (2-325): 8.99e-34: 128: 18.24		UB2E1_HUMAN (3-156): 7.23e-67: 203: 33.12
+	Hs
		282716 RNF8_HUMAN (99-318): 1.65e-29: 119: 16.02		UB2E2_HUMAN (3-156): 7.29e-69: 208: 33.77
+	Hs
		282705 RNF8_HUMAN (99-318): 1.65e-29: 119: 16.02		UB2E3_HUMAN (3-156): 2.14e-68: 207: 33.77
+	Hs
		282582 RNF8_HUMAN (99-318): 1.65e-29: 119: 16.02		UB2E1_HUMAN (3-156): 7.23e-67: 203: 33.12
+	Sc
		969186 PEX10_YEAST (6-324): 3.9e-51: 174: 22.86		UBC7_YEAST (1-149): 9.95e-31: 110: 38.13