HitPredict

Interactor 1: IMA7 (O60684)
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Gene: KPNA6

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27705803
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 183
+	Hs
		134888 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		238657 IMA7_HUMAN (1-536): 7e-160: 467: 100.00		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		134845 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		134876 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		131397 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		131416 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		800322 IMA1_HUMAN (1-536): 5.59e-142: 421: 44.92		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		853239 IMA1_HUMAN (1-536): 5.59e-142: 421: 44.92		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	At
		1276955 IMPA1_ARATH (3-536): 1.3e-158: 464: 53.43		LHP1_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		984992 IMPA1_ARATH (3-536): 1.3e-158: 464: 53.43		Q058P7_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		285377 IMPA4_ARATH (3-536): 8.6e-156: 457: 53.06		Q058P7_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		285382 IMPA4_ARATH (3-536): 8.6e-156: 457: 53.06		LHP1_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		1276959 IMPA6_ARATH (3-536): 2.54e-153: 451: 50.28		LHP1_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		97779 IMPA2_ARATH (3-536): 2.13e-153: 451: 53.43		Q058P7_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		97806 IMPA2_ARATH (3-536): 2.13e-153: 451: 53.43		LHP1_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		984993 IMPA6_ARATH (3-536): 2.54e-153: 451: 50.28		Q058P7_ARATH (23-116): 1.44e-23: 98: 31.58