Interactor 1: IMA7 (O60684)
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Gene: KPNA6

Interactor 2: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.534

The method score is based on:

Property Details
Experiments 34950606
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:1900017 - positive regulation of cytokine production involved in inflammatory response
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 536
Hs

1 427
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024