Interactor 1: IMA7 (O60684)
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Gene: KPNA6

Interactor 2: IMB1 (Q14974)
Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
Gene: KPNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.871

The method score is based on:

Property Details
Experiments 26496610, 35271311, 10523667
Identification Methods affinity chromatography technology, pull down, surface plasmon resonance, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT_EZ~IBB, IBB~IBN_N
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus
GO:0006607 - NLS-bearing protein import into nucleus
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 536
Hs

1 876
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024