HitPredict

Interactor 1: LPXN (O60711)
Leupaxin
Gene: LPXN

Interactor 2: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007155 - cell adhesion GO:0030036 - actin cytoskeleton organization GO:0031941 - filamentous actin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 386 Hs			1 1117
+	Hs
		549182 ZN250_HUMAN (32-351): 4.37e-54: 189: 10.74		CYTSA_HUMAN (1-1117): 1.12e-71: 262: 100.00
+	Hs
		1148979 PDLI7_HUMAN (266-385): 9.48e-30: 121: 32.50		CYTSA_HUMAN (1-1117): 1.12e-71: 262: 100.00
+	Hs
		521553 ZYX_HUMAN (270-385): 2.11e-29: 121: 31.09		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Hs
		521623 PDLI7_HUMAN (266-385): 9.48e-30: 121: 32.50		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Hs
		725659 ZYX_HUMAN (270-385): 2.11e-29: 121: 31.09		ACTN2_HUMAN (1009-1115): 3.7e-48: 188: 41.67
+	Hs
		725704 PDLI7_HUMAN (266-385): 9.48e-30: 121: 32.50		ACTN2_HUMAN (1009-1115): 3.7e-48: 188: 41.67
+	Hs
		211588 ZYX_HUMAN (270-385): 2.11e-29: 121: 31.09		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		211672 PDLI7_HUMAN (266-385): 9.48e-30: 121: 32.50		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		150533 ABLM1_HUMAN (134-318): 2.34e-39: 151: 29.65		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		521634 TES_HUMAN (286-386): 7.15e-23: 101: 31.37		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Hs
		211685 TES_HUMAN (286-386): 7.15e-23: 101: 31.37		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Dm
		54833 ZASP_DROME (268-384): 1.43e-12: 71.6: 30.25		ACTN_DROME (1009-1116): 2.32e-50: 195: 37.62
+	Hs
		725036 PDLI7_HUMAN (266-385): 9.48e-30: 121: 32.50		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Ce
		107555 G5EFG1_CAEEL (267-384): 1.48e-12: 70.9: 30.83		H2L2C8_CAEEL (1009-1116): 1.45e-49: 192: 43.12
+	Mm
		1186636 PDLI5_MOUSE (324-385): 5.72e-12: 69: 35.48		ACTN1_MOUSE (1009-1116): 1e-49: 193: 42.20
+	Mm
		1337461 LDB3_MOUSE (325-385): 1.97e-11: 67.5: 39.34		ACTN2_MOUSE (1009-1115): 4.42e-48: 187: 41.67
+	Ce
		107755 G5EFL5_CAEEL (325-385): 2.21e-10: 64.4: 34.92		Q23158_CAEEL (1009-1116): 1.02e-46: 184: 40.37
+	Hs
		522595 LIMS1_HUMAN (136-266): 1.65e-27: 112: 34.09		MYH7_HUMAN (2-615): 3.07e-22: 106: 8.32
+	Hs
		816296 LIMS1_HUMAN (136-266): 1.65e-27: 112: 34.09		MYH4_HUMAN (5-608): 1.24e-21: 104: 9.44
+	Hs
		506846 PDLI7_HUMAN (266-385): 9.48e-30: 121: 32.50		SPTB1_HUMAN (1012-1115): 7.3e-16: 85.5: 47.62