HitPredict

Interactor 1: LPXN (O60711)
Leupaxin
Gene: LPXN

Interactor 2: LPP (Q93052)
Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma)
Gene: LPP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0001725 - stress fiber GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 386 Hs			1 612
+	Hs
		238967 LPXN_HUMAN (9-326): 2.55e-44: 159: 23.44		ZYX_HUMAN (112-602): 2.37e-101: 321: 36.03
+	Hs
		200167 TGFI1_HUMAN (1-385): 5.05e-86: 270: 44.44		PAXI_HUMAN (2-601): 1.27e-57: 205: 15.60
+	Hs
		150579 ABLM1_HUMAN (134-318): 2.34e-39: 151: 29.65		ZYX_HUMAN (112-602): 2.37e-101: 321: 36.03
+	Hs
		1044598 FHL3_HUMAN (123-320): 2.53e-41: 148: 27.45		ZYX_HUMAN (112-602): 2.37e-101: 321: 36.03
+	Hs
		238998 LPXN_HUMAN (9-326): 2.55e-44: 159: 23.44		LIMD1_HUMAN (25-604): 4.56e-69: 238: 23.63
+	Hs
		301018 ABLM3_HUMAN (210-384): 6.42e-39: 149: 23.66		LIMD1_HUMAN (25-604): 4.56e-69: 238: 23.63
+	Hs
		150539 ABLM1_HUMAN (134-318): 2.34e-39: 151: 29.65		PAXI_HUMAN (2-601): 1.27e-57: 205: 15.60
+	Hs
		150570 ABLM1_HUMAN (134-318): 2.34e-39: 151: 29.65		FHL2_HUMAN (378-612): 8.18e-55: 189: 21.43
+	Hs
		1044590 FHL3_HUMAN (123-320): 2.53e-41: 148: 27.45		FHL2_HUMAN (378-612): 8.18e-55: 189: 21.43
+	Hs
		200190 TGFI1_HUMAN (1-385): 5.05e-86: 270: 44.44		TES_HUMAN (529-612): 2.14e-09: 62: 17.86
+	Hs
		823405 ZYX_HUMAN (270-385): 2.11e-29: 121: 31.09		PAXI_HUMAN (2-601): 1.27e-57: 205: 15.60
+	Hs
		238966 LPXN_HUMAN (9-326): 2.55e-44: 159: 23.44		TRIP6_HUMAN (1-527): 2.14e-19: 93.5: 21.52
+	Hs
		549178 ZN250_HUMAN (32-351): 4.37e-54: 189: 10.74		FHL5_HUMAN (442-610): 9.48e-09: 58.9: 26.97
+	Hs
		1136570 FHL5_HUMAN (175-385): 6.21e-55: 184: 25.58		FHL5_HUMAN (442-610): 9.48e-09: 58.9: 26.97
+	Hs
		1044595 FHL3_HUMAN (123-320): 2.53e-41: 148: 27.45		TRIP6_HUMAN (1-527): 2.14e-19: 93.5: 21.52
+	Hs
		1044587 FHL3_HUMAN (123-320): 2.53e-41: 148: 27.45		FHL3_HUMAN (440-572): 8.41e-12: 68.2: 32.35
+	Hs
		1076405 ZYX_HUMAN (270-385): 2.11e-29: 121: 31.09		TRIP6_HUMAN (1-527): 2.14e-19: 93.5: 21.52
+	Hs
		1044729 FHL3_HUMAN (123-320): 2.53e-41: 148: 27.45		TES_HUMAN (529-612): 2.14e-09: 62: 17.86