HitPredict

Interactor 1: LPXN (O60711)
Leupaxin
Gene: LPXN

Interactor 2: ATX2 (Q99700)
Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)
Gene: ATXN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 386 Hs			1 1313
+	Hs
		1044689 FHL3_HUMAN (123-320): 2.53e-41: 148: 27.45		ATX2_HUMAN (1-1313): 1.72e-116: 397: 100.00
+	Hs
		1044609 FHL3_HUMAN (123-320): 2.53e-41: 148: 27.45		OBSCN_HUMAN (105-1254): 3.4e-93: 335: 13.86
+	Hs
		91501 PDLI7_HUMAN (266-385): 9.48e-30: 121: 32.50		E7ET48_HUMAN (379-1312): 1.13e-14: 81.7: 8.82
+	Ce
		136803 Q3S1I9_CAEEL (129-265): 8.94e-26: 107: 24.11		UNC89_CAEEL (167-730): 2.93e-17: 90.6: 12.43
+	Hs
		1050727 FHL2_HUMAN (123-261): 2.11e-23: 100: 25.87		ATX2L_HUMAN (521-1304): 2.92e-19: 96.4: 18.02
+	Hs
		1078419 ZKSC8_HUMAN (32-208): 2.52e-24: 106: 8.38		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Hs
		1050757 FHL2_HUMAN (123-261): 2.11e-23: 100: 25.87		MINT_HUMAN (431-1274): 9.87e-12: 72.1: 8.75
+	Hs
		1050839 FHL2_HUMAN (123-261): 2.11e-23: 100: 25.87		MAGL2_HUMAN (3-790): 2.5e-09: 64: 8.25
+	Ce
		107557 G5EFG1_CAEEL (267-384): 1.48e-12: 70.9: 30.83		UNC89_CAEEL (167-730): 2.93e-17: 90.6: 12.43
+	Hs
		1293388 PDLI5_HUMAN (324-385): 2.62e-12: 70.2: 35.48		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47