HitPredict

Interactor 1: CTND1 (O60716)
Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))
Gene: CTNND1

Interactor 2: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30639242, 30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 968 Hs			1 189
+	Hs
		239016 CTND1_HUMAN (1-968): 0: 939: 100.00		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		239015 CTND1_HUMAN (1-968): 0: 939: 100.00		RASN_HUMAN (1-189): 2.37e-85: 251: 85.19
+	Hs
		239136 CTND1_HUMAN (1-968): 0: 939: 100.00		RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28
+	Hs
		239101 CTND1_HUMAN (1-968): 0: 939: 100.00		RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97
+	Hs
		239109 CTND1_HUMAN (1-968): 0: 939: 100.00		RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88
+	Hs
		119748 ARVC_HUMAN (1-930): 0: 613: 46.27		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		119749 ARVC_HUMAN (1-930): 0: 613: 46.27		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		1070365 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28
+	Hs
		350487 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		895244 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97
+	Hs
		914314 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88
+	Hs
		349752 PKP3_HUMAN (39-852): 7.04e-141: 442: 24.40		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		349025 PKP3_HUMAN (39-852): 7.04e-141: 442: 24.40		RASN_HUMAN (1-189): 2.37e-85: 251: 85.19
+	Hs
		350719 PKP3_HUMAN (39-852): 7.04e-141: 442: 24.40		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		349154 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		RASH_HUMAN (1-188): 6.53e-87: 255: 86.77
+	Hs
		348538 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		RASN_HUMAN (1-189): 2.37e-85: 251: 85.19
+	Hs
		717100 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28
+	Hs
		349923 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00
+	Hs
		716953 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88
+	Hs
		349846 PLAK_HUMAN (169-906): 2.02e-105: 346: 15.85		RASK_HUMAN (1-189): 8.4e-77: 229: 100.00