HitPredict

Interactor 1: CTND1 (O60716)
Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))
Gene: CTNND1

Interactor 2: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	12640114, 12835311
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0098685 - Schaffer collateral - CA1 synapse
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 968 Hs			1 537
+	Hs
		239035 CTND1_HUMAN (1-968): 0: 939: 100.00		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		239025 CTND1_HUMAN (1-968): 0: 939: 100.00		YES_HUMAN (1-537): 0: 591: 71.61
+	Hs
		239023 CTND1_HUMAN (1-968): 0: 939: 100.00		LCK_HUMAN (40-535): 0: 551: 57.60
+	Hs
		239026 CTND1_HUMAN (1-968): 0: 939: 100.00		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		239089 CTND1_HUMAN (1-968): 0: 939: 100.00		BLK_HUMAN (28-532): 2.42e-179: 515: 56.72
+	Hs
		239072 CTND1_HUMAN (1-968): 0: 939: 100.00		TEC_HUMAN (5-529): 6.12e-163: 478: 34.89
+	Hs
		411837 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		LCK_HUMAN (40-535): 0: 551: 57.60
+	Hs
		433972 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		412054 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		FYN_HUMAN (1-537): 0: 643: 100.00
+	Hs
		522819 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		433616 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		411579 PLAK_HUMAN (169-906): 2.02e-105: 346: 15.85		LCK_HUMAN (40-535): 0: 551: 57.60
+	Hs
		433555 PLAK_HUMAN (169-906): 2.02e-105: 346: 15.85		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		337371 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56
+	Hs
		411829 PKP4_HUMAN (8-353): 3.73e-18: 92.4: 16.20		LCK_HUMAN (40-535): 0: 551: 57.60
+	Hs
		433962 PKP4_HUMAN (8-353): 3.73e-18: 92.4: 16.20		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		433584 APC_HUMAN (390-589): 9.85e-10: 65.2: 22.71		LYN_HUMAN (1-535): 0: 535: 54.48