HitPredict

Interactor 1: CTND1 (O60716)
Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))
Gene: CTNND1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030426 - growth cone and 1 others more... GO:0043197 - dendritic spine
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 968 Hs			1 758
+	Hs
		239044 CTND1_HUMAN (1-968): 0: 939: 100.00		MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84
+	Hs
		496430 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496219 PLAK_HUMAN (169-906): 2.02e-105: 346: 15.85		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		582019 PLAK_RAT (169-906): 7.4e-107: 350: 15.72		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94245 PLAK_RAT (169-906): 7.4e-107: 350: 15.72		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		152599 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		554276 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84
+	Dm
		578747 ARM_DROME (164-876): 2.91e-114: 373: 18.21		Q9VPR2_DROME (127-757): 2.65e-20: 98.2: 10.23
+	Hs
		542170 PLAK_HUMAN (169-906): 2.02e-105: 346: 15.85		MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84
+	Hs
		134829 IMA3_HUMAN (591-962): 6.22e-41: 160: 10.34		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		238627 IMA7_HUMAN (497-951): 5.76e-29: 124: 9.61		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497820 CTND2_HUMAN (2-379): 2e-17: 90.1: 18.62		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		554267 APC_HUMAN (390-589): 9.85e-10: 65.2: 22.71		MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84
+	Hs
		626277 APC_HUMAN (390-589): 9.85e-10: 65.2: 22.71		YM012_HUMAN (3-484): 1.7e-24: 110: 8.67