HitPredict

Interactor 1: CTND1 (O60716)
Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))
Gene: CTNND1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome GO:0098685 - Schaffer collateral - CA1 synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 968 Hs			1 196
+	Hs
		239111 CTND1_HUMAN (1-968): 0: 939: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		239102 CTND1_HUMAN (1-968): 0: 939: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		239040 CTND1_HUMAN (1-968): 0: 939: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		239028 CTND1_HUMAN (1-968): 0: 939: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		239115 CTND1_HUMAN (1-968): 0: 939: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		239100 CTND1_HUMAN (1-968): 0: 939: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		239045 CTND1_HUMAN (1-968): 0: 939: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120234 CTND1_HUMAN (1-968): 0: 939: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Mm
		677654 CTND1_MOUSE (1-937): 0: 894: 97.65		RHOA_MOUSE (1-196): 3.27e-78: 233: 83.16
+	Hs
		119765 ARVC_HUMAN (1-930): 0: 613: 46.27		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		925563 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900842 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915921 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		892562 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		894360 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Dm
		816378 Q7PLI0_DROME (132-893): 9.23e-145: 451: 30.86		RHO1_DROME (1-196): 5.31e-75: 225: 80.10
+	Hs
		545714 PKP3_HUMAN (39-852): 7.04e-141: 442: 24.40		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		894615 PKP3_HUMAN (39-852): 7.04e-141: 442: 24.40		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Mm
		925786 CTNB1_MOUSE (156-923): 6.19e-114: 370: 16.81		RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10
+	Hs
		120321 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98