HitPredict

Interactor 1: CTND1 (O60716)
Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))
Gene: CTNND1

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 20562859
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome GO:0140311 - protein sequestering activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 968 Hs			1 440
+	Hs
		717058 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		239168 CTND1_HUMAN (1-968): 0: 939: 100.00		MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19
+	Hs
		134891 IMA3_HUMAN (591-962): 6.22e-41: 160: 10.34		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		319734 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		542324 PLAK_HUMAN (169-906): 2.02e-105: 346: 15.85		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78