HitPredict

Interactor 1: PLPL9 (O60733)
85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (2-lysophosphatidylcholine acylhydrolase) (EC 3.1.1.5) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9)
Gene: PLA2G6

Interactor 2: SRBP1 (P36956)
Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1 (Transcription factor SREBF1)]
Gene: SREBF1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15450207
Identification Methods	electrophoretic mobility shift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 1147
+	Hs
		239456 PLPL9_HUMAN (1-806): 0: 587: 100.00		SRBP2_HUMAN (6-1147): 0: 962: 43.61
+	Dm
		1361443 Q9VAU5_DROME (4-772): 5.86e-132: 435: 13.49		Q9VLS7_DROME (4-489): 8.29e-11: 68.9: 10.66
+	Mm
		103609 ANK3_MOUSE (4-239): 1.6e-49: 191: 18.52		MICA3_MOUSE (36-538): 6.55e-26: 118: 14.74
+	Dm
		1182373 Q7KU92_DROME (248-672): 7.91e-65: 238: 13.32		Q9VLS7_DROME (4-489): 8.29e-11: 68.9: 10.66
+	Dm
		1362722 ANKHM_DROME (14-208): 1.31e-27: 122: 9.95		Q9VLS7_DROME (4-489): 8.29e-11: 68.9: 10.66
+	Hs
		276200 PSD10_HUMAN (222-404): 1.65e-15: 78.6: 31.18		CBP_HUMAN (18-407): 2.51e-10: 67.3: 12.37